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Editorial |
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Regional anaesthesia in children: pros and cons
Shahla Siddiqui,
Regional Anaesthesia, as an adjunct to General anaesthesia (GA) for intraoperative and sometimes postoperative analgesia, is a common and accepted standard of care in paediatric and neonatal surgery.1 Most frequently these include caudal, ilioinguinal/ iliohypogastric or sp....
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Original Articles |
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Study on the changes of Carbonic Anhydrase activity in insulin resistance and the effect of methylglyoxal
Utpal Kumar Biswas,
Arun Kumar,
Objectives: To determine the serum levels of methylglyoxal (MG) and carbonic anhydrase (CA) activity in known cases of type-II diabetes mellitus with insulin resistance and to compare them with age-sex matched healthy controls.
Methods: Eightysix participants were enrolled fo....
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Gender differences of heart rate variability in healthy volunteers
Shemaila Saleem,
Muhammad Mazhar Hussain,
Syed Muhammad Imran Majeed,
Muhammad Alamgir Khan,
Objective: To identify the basic values of heart rate variability in Pakistani population and to verify our hypothesis that there are gender differences in cardiovascular autonomic modulation.
Methods: The descriptive cross sectional study based on convenience probability sam....
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Drug utilization patterns in Rawalpindi and Islamabad, Pakistan
Muhammad Asif Nasir,
Ramiz Iqbal Hashmi,
Naseem Saud Ahmad,
Objectives: To assess the prevalence of self medication among Pakistanis in rural and urban settings.
Methods: A door-to-door survey was carried out during June and July 2008 and 2009 after due verbal consent taken from the residents. The houses were randomly selected from ul....
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A retrospective study of cardiotoxicities induced by 5-Fluouracil (5-FU) and 5-FU based chemotherapy regimens in Pakistani adult cancer patients at Shaukat Khanum Memorial Cancer Hospital & Research Center
Mansoor Ahmed Khan,
Nehal Masood,
Nawazishi Husain,
Bashir Ahmad,
Tahir Aziz,
Anjum Naeem,
Objective: To study cardiotoxicities, especially bradycardia in cancer patients treated with 5-Fluouracil and 5-Fluouracil based chemotherapy regimens in Pakistani population.
Methods: Data was extracted from the medical records of all diagnosed cancer patients at Shaukat Kha....
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High prevalence of obesity in Tokat, a northern province of Turkey
Yusuf Ustu,
Mehmet Ugurlu,
Ozlem Aslan,
Yasar Metin Aksoy,
Ismail Kasim,
Mehmet Taskin Egici,
SelimYavuz Sanisoglu,
Objective: To determine the prevalence of overweight and obesity in the Tokat Region with demographic, socioeconomic and medical factors in the adult population.
Methods: A sample was selected from the province of Tokat. A total of 5162 participants over 18 years (1885 women ....
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Neuraxial block versus general anaesthesia for cesarean section: post-operative pain scores and analgesic requirements
Kemal Tolga Saracoglu,
Ayten Saracoglu,
Tumay Umuroglu,
Zeynep Eti,
Objective: To evaluate the suitability of spinal and general anaesthesia for cesarean section.
Methods: The prospective, double-blinded study, done between March and December 2009, at Central Education and Research Hospital, Erzurum, Turkey, involved 60 patients undergoing el....
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The rationality of prescribing antibiotics after tonsillectomy
Maqbool Ahmed Baloch,
Shabbir Akhtar,
Mubasher Ikram,
Hassan Nabeel Humayun,
Objective: To compare the antibiotic therapy with the absence of antibiotic therapy in reducing post-tonsillectomy morbidities
Methods: The quasi-experimental study was conducted at the Aga Khan University Hospital, Karachi, from November 2006 to September 2007. It involved 6....
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Clinical results of the intra-cytoplasmic sperm injection with surgically retrieved sperms in azoospermic men at Sindh Institute of Reproductive Medicine, Karachi
Majida Khan,
Shaheen Zafar,
Aziz Abdullah,
Ahmed Fawad,
Serajuddaula Syed,
Objective: To analyse the result of intra-cytoplasmic sperm injection (ICSI) by using surgically retrieved sperms in the azoospermic male.
Methods: Eight (9 cycles) azoospermic men were given the intra-cytoplasmic sperum injection after sperms were collected through surgical ....
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Association between puberty and weight, height and Body Mass Index in a developing community
Hamidreza Bazrafshan,
Naser Behnampour,
Farhad Sarabandi,
Sahar Mirpour,
Objective: To evaluate the epidemiology of pubertal development of girls in a developing community.
Methods: The cross-sectional study was undertaken in July 2005, on 788 healthy 7-16 years old girls in Gorgan, the most populous city of Golestan province in northern Iran. Phy....
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Daycare adeno-tonsillectomy: Is it safe in developing countries?
Aria Masoom,
Shabbir Akhtar,
Hassan Nabeel Humayun,
Mubasher Ikram,
Objective: To determine the safety of daycare adeno-tonsillectomy in a tertiary care centre.
Method: A retrospective chart review of 207 patients who had undergone tonsillectomy and/or adenoidectomy as daycare procedure in Aga Khan University Hospital, Karachi, between Januar....
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Comparison of diagnostic value of conventional ultrasonography by emergency physicians with doppler ultrasonography by radiology physicians for diagnosis of deep vein thrombosis
Saeed Abbasi,
Ehsan Bolverdi,
Mohammad Amin Zare,
Peyman Hafezimoghadam,
Marzieh Fathi,
Davood Farsi,
Mehrdad Moghimi,
Objectives: To determine sensitivity, specificity and other operating characteristics of bedside three-point compression ultrasonography performed in emergency department by emergency physicians in comparison with duplex ultrasonography.
Methods: The cross-sectional study at ....
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Stomal recurrence after total laryngectomy: a 10-year review in Universiti Kebangsaan Malaysia Medical Center
Nur Hashima bte Abdul Rashid,
Mohd Razif bin Mohamad Yunus,
Marina Mat bte Baki,
Mazita bte Ami,
Primuharsa Putra bin Sabir Husin Athar,
Objective: To determine the frequency of stomal recurrence in patients following total laryngectomy in our center and to compare the frequency of previously reported risk factors such as preoperative tracheostomy, subglottic invasion and the level of lymph node metastases, with the rest of....
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Role of endovascular treatment in vascular injuries
Muhammad Misbah Tahir,
Tanveer-ul-Haq,
Objective: To evaluate retrospectively the results, complications and follow-up of patients after endovascular treatment of vascular injuries.
Methods: Fifty transcatheter embolisation procedures (TCE) were performed in 46 patients between 1999 and 2008 at the Aga Khan Univer....
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Foetal outcome in patients with Meconium Stained Liquor
Rekha Kumari,
Pushpa Srichand,
Bikha Ram Devrajani,
Syed Zulfiquar Ali Shah,
Tarachand Devrajani,
Ishrat Bibi,
Rattan Kumar,
Objective: To determine the foetal outcome and mode of delivery in patients with meconium stained liquor during labour.
Methods: The observational study was carried out at the Obstetrics and Gynaecology Unit-II of Liaquat University of Medical Health Sciences from June to Nov....
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Review Articles |
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Guidelines on the laboratory diagnosis of congenital bleeding disorders in Pakistan
Munira Borhany,
Tahir Shamsi,
Bushra Moiz,
Khalid Hasan,
Khalid Zafar Hashmi,
Muhammad Ayyub,
Nadir Ali,
Nisar Ahmed Samina Amanat,
Tahira Zafar,
Congenital bleeding disorders are found in all racial groups and are present worldwide. Among all of them haemophilia A, B and Von Willebrand\'s disease are the commonest and they are characterized by the low blood levels of factor VIII, IX and Von Willebrand\'s factor respectively. Severity ....
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Case Reports |
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Pulmonary Hyalinising Granuloma: A rare pulmonary disorder
Arsalan Rahatullah,
Zeeshan Waheed,
Javaid A Khan,
Nasir-ud-Din,
Pulmonary hyalinising granulomas are rare, non-infectious fibrosclerosing lesions of the lung which can mimic metastatic disease. It was first described in literature by Engleman et al in the year 1977. Its etiology is unknown but they may be caused by an exaggerated immune response. The patient ....
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Recurrent urinary tract infection by Burkholderia cepacia in a live related renal transplant recipient
Mohammad Zeeshan,
Tahir Aziz,
Farah Naqvi,
Burkholderia cepacia is high virulent organism usually causing lower respiratory tract infections especially in Cystic fibrosis (CF) patients and post lung transplant. Urinary tract infections with Burkholderia cepacia have been associated after bladder irrigation or use of contaminated hospital ....
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Intraareolar polythelia: a rare anomaly
Rustu Kose,
Abdullah Ozgoonul,
Ismet Bingol,
Polythelia, the presence of supernumerary nipples or nipple-areola complexes, is the most common anomaly of the pediatric breast. Although polythelia is common, intraareolar polythelia (nipple dichotomy) is an extremely rare congenital malformation. Surgical treatment is performed as a prophylaxi....
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Erosive pustular dermatosis of the scalp
Sergio Vano-Galvan,
Martorell-Calatayud Antonio,
Jaen Pedro,
Erosive pustular dermatosis of the scalp is a rare condition characterized by sterile pustules, erosions and crusted lesions on the scalp of elderly patients. It can be misdiagnosed with tinea capitis or even skin cancer, so it is important to be aware of this entity for a correct diagnosis.
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Giant Pulmonary Bulla with Mediastinal Shift in a 12 ˝ year old girl
Saulat Hasnain Fatimi,
Asif Jafferani,
Awais Ashfaq,
Pulmonary bulla in children represent interesting entities. Mostly congenital bronchopulmonary foregut malformations and acquired cysts like pneumatocoeles have also been described. We present a case of a 12 ˝ years old girl with acute onset respiratory distress symptoms harbouring a huge ....
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Aromatase inhibitors — a viable option for recurrent granulosa cell tumour of ovary: overview and case report
Assam Abdul Munem,
Bassim Al-Bahrani,
Itrat Mehdi,
Atheel Kamona,
Ayman Mohammad Nada,
Granulosa cell tumour of the ovary in adults is a rare tumour of low malignant potential affecting middle aged peri or post menopausal patients. These tumours are often diagnosed at an early stage, due to their hormonally active nature. They, however, have unique distinguishing histologic feature....
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Mixed constrictive pericarditis and restrictive cardiomyopathy in a 36-year-old female
Naveed Akhtar,
Ayesha Khalid,
Sabeen Razaque,
Waqas Ahmed,
Habib-ur-Rahman,
Munir Ahmed,
Mixed lesion of Restrictive Cardiomyopathy and Constrictive Pericarditis is a rarely reported clinical entity which poses a diagnostic and therapeutic enigma to physicians. The management of both conditions differs markedly. Restrictive Cardiomyopathy is managed either conservatively or cardiac t....
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Opinion and Debate |
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Light therapy: Does it play an important role in Mental Health?
Amin A. Muhammad Gadit,
According to Lam1 based on his observations, research and literature review, initial use of light therapy in psychiatry arose from circadian rhythm hypotheses for seasonal and non-seasonal depression. Suppression of human melatonin generally requires greater than 2,000 lux ....
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Student's Corner |
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Current understanding of treatment and management protocol for adult diabetic in-patients at a tertiary care hospital
Nida Waki,
Adil Memon,
Muhammad Owais Khan,
Hina Faruqi,
Sara Masood,
Mariam Rauf,
Rabeea Mirza,
Samrah Zaigham,
Fatima Asgher,
Hira Amjad,
Urooba Nadeem,
Sadia Farooq,
Haroon Ali,
Fuad Sheikh,
Objective: To assess the current understanding of treatment and management protocols for adult diabetic in-patients at a tertiary care hospital.
Methods: This cross-sectional study, conducted at the Civil Hospital Karachi from July to September 2009, involved 450 participants....
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Acetaminophen induced Steven Johnson Syndrome-Toxic Epidermal Necrolysis overlap
Ali Khawaja,
Ahmed Shahab,
Syed Ather Hussain,
Steven Johnson Syndrome and Toxic Epidermal Necrolysis are rare but severe form of hypersensitivity inflammatory reactions to multiple offending agents including drugs. Acetaminophen is extensively used due to its analgesic and anti-pyretic properties. It is rendered to be relatively safe, with h....
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Medical students and medical research in Pakistan
Madam, South Asia contributes to only 1.2% of research articles despite being one-fifth of the world\'s population. The situation is worse, particularly in Pakistan where there is a notable lack of physician-scientists.1 One of the main culprits could be lack of research ....
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Letter to the Editor |
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Critical care evolves to become patient-centred rather than clinician-based
Madam, critical care has evolved in the past few decades to become patient-centred rather than clinician- based. In 2007, the American College of Critical Care Medicine task force published forty-three recommendations, endorsing a shared decision-making model which incorporates the family-centred....
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How to improve medical reading in Pakistani doctors?
Madam, we have read "Readers are leaders in publishing"1 by Ejaz et al with interest. They have highlighted an aspect that is generally not emphasized at the undergraduate and post graduate medical education system in Pakistan. But this problem is not limited to P....
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Short Review |
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Triage; a literature review of key concepts
Khairulnissa Ajani,
The emergency department (ED) - sometimes termed the emergency room (ER), or the accident & emergency (A&E) department - in a hospital or primary care facility that provides initial treatment to patients with a broad spectrum of illnesses and injuries, some of which may be life-threatenin....
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Evidence Based Medicine |
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What is the role of free radical scavengers in acute stroke?
Muhammad Faisal Wadiwala,
Ambreen Sonawalla,
Ayeesha Kamran Kamal,
Effects of Edaravone, a Free Radical Scavenger, on Serum Levels of Inflammatory Biomarkers in Acute Brain Infarction.
Why is this study important and noteworthy?
Stroke may lead to functional disability. Much of this tissue injury is a result of the release of free radicals, ....
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Learning Research |
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Questionnaire designing and validation
Abdul Momin Kazi,
Wardah Khalid,
Introduction and Objectives:
Measurement is an essential activity of medical science. In order to acquire data about people, objects, and events proper data collection tools need to be designed which can measure things of scientific interest. Questionnaire is one of the most importa....
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News & Events |
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Index |
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Supplement |
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Issue Vol:62, No:5 May, 2012