Welcome to Journal Of Pakistan Medical Association
   Issue Vol:67, No:7 July, 2017
Editorial >>

Premarital health and social issues in Pakistan

Sadiah Ahsan Pal.

Lack of formal reproductive health education in educational institutions in Pakistan and social taboos, leaves the majority of newly married couples unprepared to deal with sexual, social and health issues after marriage.
Early age marriage is prevalent in our society where 35% get married

Original Articles >>

Yield of 48-hour Holter monitoring in children with unexplained palpitations and significance of associated symptoms

Rabbia Aman, Ahmad Usaid Qureshi, Masood Sadiq.

Objective: To determine the yield of 48-hour Holter monitoring in children with unexplained palpitations and the significance of associated symptoms.
Methods: This descriptive study was conducted at the Children\'s Hospital and Institute of Child Health, Lahore, Pakistan, f

Association of Interferon Alpha Receptor 1 with sustained virological response in hepatitis C and B co-infected patients

Maleha Asim, Amir Rashid, Asifa Majeed, Maryam Wahid, Suhail Razak, Aneela Jamil.

Objective: To determine the association of interferon alpha receptor-1 with success rate of interferon therapy in patients co-infected with hepatitis C virus and hepatitis B virus.
Methods: The study was conducted at the Army Medical College, Rawalpindi, Pakistan, from Decemb

Prevalence and antifungal susceptibility of Candida species in a tertiary care hospital in Islamabad, Pakistan

Umber Tasneem, Maryam Tahir Siddiqui, Rani Faryal, Aamer Ali Shah.

Objective: To determine the prevalence and antifungal susceptibility pattern of Candida species.
Methods: This prospective, cross-sectional study was conducted at the Quaid-e-Azam International Hospital, Islamabad, Pakistan, from January 2014 to February 2015, and comprised d

Impact of social interdependence on emotional well-being of medical students

Shaahjahan Katpar, Zohaib Rana, Mehwish Hussain, Rakhshaan Khan, Rehana Rehman.

Objective: To observe the effect of social interdependence on emotional well-being in medical students.
Methods: This cross-sectional study was conducted in Karachi from June 2013 to January 2014 and comprised first-year medical students of 5 private and 3 public-sector colle

Levels of platelet-derived microparticles and soluble p-selectin in patients of acute myocardial infarction (case control study)

Aisha Hameed, Zille Rubab, Syed Khizar Abbas Rizvi, Shabbir Hussain, Waqas Latif, Shahida Mohsin.

Objective: To measure levels of platelet-derived microparticles and soluble P-selectin in patients of acute myocardial infarction and their comparison with healthy controls.
Methods: This case-control study was conducted in Department of Haematology, University of Health Scie

Assessment of the underlying causes of the immune thrombocytopenia: Ten years experience

Mehmet Sinan Dal, Abdullah Karakus, Tuba Dal, Berrin Balik Aydin, Elif Hattapoglu, Mehmet Onder Ekmen, Turgay Ulas, Orhan Ayyildiz.

Objective: Immune thrombocytopenia (ITP) is an immune haematologic disorder causing platelet destruction mediated by anti-platelet antibodies. In this study we aimed to evaluate the clinical and laboratory variables of ITP patients in southeast of Turkey.
Methods: In this ret

Frequency and associated risk factors for neck pain among software engineers in Karachi, Pakistan

Mohammad Rasim ul Hasanat, Syed Shahzad Ali, Abdur Rasheed, Muhammad Khan.

Objective: To determine the frequency of neck pain and its association with risk factors among software engineers.
Methods: This descriptive, cross-sectional study was conducted at the Dow University of Health Sciences, Karachi, from February to March 2016, and comprised soft

Who teaches science to nurses?

Naghma Rizvi.

Objective: To explore the demographics of individuals teaching basic science courses in private nursing schools.
Methods: The study was conducted in Karachi, and comprised teachers teaching basic science courses in 16 registered private nursing schools. A demographic question

Incidence and pattern of Thrombocytopenia in cardiac surgery patients

Mohammad Hamid, Mohammad Irfan Akhtar, Hamid Iqil Naqvi, Khalid Ahsan.

Objective: To observe the incidence and pattern of thrombocytopenia in cardiac surgery patients.
Methods: This prospective, cohort study was conducted at the Aga Khan University Hospital, Karachi, from November 2014 to April 2015, and comprised adult cardiac patients. Patient

Prevalence and determinants of tobacco use among school going adolescents in Cambodia and Vietnam: a cross-sectional study

Karl Peltzer, Supa Pengpid.

Objective: To investigate the prevalence and correlates of tobacco use among school-going adolescents.
Methods: This cross-sectional study consisted of a secondary analysis of existing cross-sectional survey data from the Global School-based Health Survey from Cambodia and Vi

Molecular genetics and prenatal diagnosis of beta thalassemia to control transfusion dependent births in carrier Pakistani couples

Sumaira Kanwal, Sehrish Bukhari, Shazia Perveen.

Objective: To examine molecular genetics and prenatal diagnosis of beta-thalassaemia.
Methods: The study was conducted at the COMSATS Institute of Information Technology, Sahiwal, Pakistan, from October 2012 to October 2013, and comprised families having children affected by

Visual outcome in patients of keratomycosis, at a tertiary care centre in Larkana, Pakistan

Syed Imtiaz Ali Shah, Shujaat Ali Shah, Partab Rai, Naeem Akhtar Katpar, Safdar Ali Abbasi, Akbar Ali Soomro.

Objective: To study the post-treatment visual outcome of fungal keratitis.
Methods: This prospective study was carried out at Chandka Medical College and Hospital, Larkana, Pakistan, from March 2005 to March 2016. Patients with clinical features of fungal keratitis, with posi

Cytogenetic bio-monitoring in fuel station attendants of Gujrat, Pakistan through buccal micronucleus cytome assay

Faiza Butt, Kausar Cheema, Numrah Nisar, Javed Qureshi.

Objective: To analyse buccal epithelial cells for scoring the frequency of cytogenetic toxicity in petrol pump workers.
Methods: The case-control study was conducted at the Lahore College for Women University, Lahore, Pakistan, from September 2014 to February 2015, and compri

Outcome of application of amniotic membrane graft in ocular surface disorders

Nargis Nizam Ashraf, Muhammad Idrees Adhi.

Objective: To determine the outcome of application of amniotic graft in ocular surface disorders.
Methods: This cross-sectional study was conducted at Dow University of Health Sciences, Karachi, from January 2010 to December 2012, and comprised patients with ocular surface di

A survey to determine motivating factors to quit opioids in treatment seekers at a tertiary care hospital

Washdev, Muhammad Iqbal Afridi.

Objective: To determine the frequency of different motivating factors to quit opioid use.
Methods: The descriptive, cross-sectional study was conducted at the Department of Psychiatry and Behavioural Sciences, Jinnah Postgraduate Medical Centre, Karachi, from August 2012 to F

Frequency of acute bacterial meningitis in children with first episode of febrile seizures

Hina Batool Siddiqui, Nighat Haider, Zarmast Khan.

Objective: To determine the frequency of acute bacterial meningitis in children with first episode of febrile seizures.
Methods: This cross-sectional study was conducted at the Polyclinic, Postgraduate Medical Institute, Islamabad, Pakistan, from December 2012 to August 2013,

Affecting factors and relationship between patients' attitudes towards the nursing profession and perceptions of nursing care in a university hospital

Tulay Sagkal Midilli, Tulay Kirmizioglu, Asli Kalkim.

Objective: To evaluate affecting factors and the relationship between patients\' attitudes towards the nursing profession and perceptions of nursing care.
Methods: This cross-sectional study was conducted at Hafsa Sultan Hospital of Celal Bayar University, Manisa, Turkey, f

Spectrum of interstitial lung disease from a tertiary care hospital in Karachi

Ali Bin Sarwar Zubairi, Maryam Hassan, Talha Shahzad, Sajjad Sarwar, Aamir Abbas, Huzaifa Ahmad, Muhammad Irfan.

Objective: To determine the clinical features and patterns of interstitial lung disease.
Methods: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised record of patients diagnosed with interstitial lung disease from January 2005 t

Review Articles >>

Cervical cancer in Pakistan: A review

Syeda Asma Batool, Sumera Sajjad, Husna Malik.

Cervix carcinoma is the second commonest condition in women under 50 years of age and third after breast and oral cavity cancers across all age groups. Though a preventable disease, the mortality rate is very high because it is an ignored ailment in Pakistan in terms of screening, prevention and

Feedback in a clinical setting: A way forward to enhance student's learning through constructive feedback

Amber Shamim Sultan, Muhammad Arif Mateen Khan.

Feedback is considered as a dynamic process in which information about the observed performance is used to promote the desirable behaviour and correct the negative ones. The importance of feedback is widely acknowledged, but still there seems to be inconsistency in the amount, type and timing of

Human epidermal growth factor (Her-2) in gastric and colorectal adenocarcinoma

Asma Shabbir, Muhammad Asif Qureshi, Talat Mirza, Abdullah Bin Khalid.

Gastrointestinal (GIT) malignancies are a substantial health concern. Most patients present to the clinics with advanced and un-resectable diseases, so it remains difficult to cure with the existing chemotherapeutic regimes. It is therefore extremely important to devise novel therapeutic targets

Short Reports >>

Effects of activity repetition training with Salat (prayer) versus task oriented training on functional outcomes of stroke

Misbah Ghous, Arshad Nawaz Malik, Mian Imran Amjad, Maria Kanwal.

Stroke is one of most disabling condition which directly affects quality of life. The objective of this study was to compare the effect of activity repetition training with salat (prayer) versus task oriented training on functional outcomes of stroke. The study design was randomized control trial

The effects of gait training with body weight support (BWS) with no body weight support (no-BWS) in stroke patients

Muhammad Asad Ullah, Hina Shafi, Ghazanfar Ali Khan, Arshad Nawaz Malik, Imran Amjad.

The purpose of this study was to measure the clinical outcomes for patients with stroke after gait training with body weight support (BWS) and with no body weight support (no-BWS).Experimental group was trained to walk by a BWS system with overhead harness (BWS group), and Control group was train

Case Reports >>

Hydrogen sulfide gas poisoning in fish garbage room: A report of a fisherman

Sadaf Sheikh, Muhammad Akbar Baig, Noman Ali, NadeemUllah Khan.

We report the case of a fisherman who was exposed to high concentrations of hydrogen sulfide (H2S) gas from the fish garbage room. The patient survived and was discharged with full recovery from the hospital. H2S is a colourless, foul smelling and highly toxic gas next to carbon monoxide, which c

Six arms mesh implant application with organ-preserving in a young patient with total pelvic organ prolapse

Gokmen Sukgen, Adem Altunkol, Deniz Abat.

Pelvic Organ Prolapse (POP) is defined as the prolapse of the pelvic organs toward or through the vaginal opening as a result of the weakening of the combination of nerves, muscles and fascia, which normally protect and support the physical position of pelvic organs. In this case report, the 30-y

Typical graves' ophthalmopathy in primary hypothyroidism

Zareen Kiran, Owais Rashid, Najmul Islam.

Graves ophthalmopathy (GO) usually occurs in a close temporal relationship with hyperthyroidism. It is rare in patients with normal thyroid function (euthyroid GO) and in patients with hypothyroid forms of thyroid autoimmune diseases (hypothyroid GO). We report a 52-years old man presenting in ou

Student's Corner >>

Traumatic dislocation of phakic anterior chamber iris-claw intraocular lens: A case report

Nauman Hashmani, Mariam Saleem, Hina Rajani, Priyanka, Sharif Hashmani.

We are presenting a traumatic dislocation of a Phakic intraocular lens (PIOL) secondary to a blunt trauma to the right eye. The patient presented with a sudden blurring of vision with no other associated injury. His slit lamp examination showed disenclavation of the temporal clip and pre-operativ

Intravenous glutathione for fair skin; to give or not to give?

Momal Jamali, Aamina Majid.

Madam, white skin in Asia has traditionally been associated with higher social status and wealth. The boom in the beauty market has been extraordinary. In India, the skin lightening cosmetic market alone is worth 1000 crore.1
Many skin lightening agents are available

Letter to the Editor >>

Probiotic yogurt effect on macronutrients ingredients, blood glucose and lipid profile in type 2 diabetes

Zahra Tazakori, Maryam Zare, Mohammad Asghari Jafarabadi.

Madam, in last decade probiotics were introduced as a useful supplement on human health. As a result lactobacilli acidofilus and bifidobacterium have been more often used in dairy products.1 It is said that Lactobacillus can reduce the transferring of triglycerides in lymph

Case Series >>

Sex cord stromal tumours of the ovary, experience at Shifa International Hospital Islamabad

Asim Qureshi, Masroor Hassan, Nadira Mamoon, Zafar Ali, Imran Nazir Ahmed.

This descriptive study was carried out at Pathology Department, Shifa International Hospital from 2007 to 2016; all sex cord stromal tumours diagnosed during this time period were included. Epithelial, germ cell and metastatic tumours were excluded from the study. A total of 1254 Ovarian tumours

Outcome of focal treatment to residual retinoblastoma after chemotherapy (Experience with Focal Treatment of Retinoblastoma)

Sumbul Kashif, Kashif Muhammad, Nisar Siyal, Mohammed Idrees Adhi.

We report a prospective case series on the anatomical, and functional outcomes, and complications of focal treatment of retinoblastoma to residual tumors in patients who had already received chemotherapy.
We examined the patients of retinoblastoma under general anaesthesia with Ret Cam II.

Perspective >>

Is breast cancer awareness campaign effective in Pakistan?

Rufina Soomro.

Objective: To assess the effectiveness of existing breast cancer awareness strategies in terms of early breast cancer detection.
Methods: This descriptive, retrospective study was conducted at the Breast Surgery department of the Liaquat National Hospital, Karachi, and compri

Recent Advances In Endocrinology >>

Vitamin D deficiency: Pragmatic suggestions for prevention and treatment

Sanjay Kalra.

Vitamin D deficiency is endemic to South Asia, and is associated with varied biochemical and clinical presentations. Health care professionals of all specialties need to ensure optimal Vitamin D level of all persons, irrespective of age or gender, to prevent the many complications that are associ

Primary Care Diabetology >>

Betel quid (Paan) and diabetes care

Sanjay Kalra, Yatan Pal Singh Balhara.

This communication focuses on an important, yet neglected, aspect of medicine, which has an impact on diabetes care as well. Betel quid (paan) chewing is a commonly encountered, socioculturally accepted, "culture-bound" addictive disorder. Betel quid chewing has unwanted psychotropic, c

Evidence Based Neuro-Oncology >>

Role of Intra-operative MRI (iMRI) in Improving Extent of Resection and Survival in Patients with Glioblastoma Multiforme

Inamullah Khan, Muhammad Waqas, Muhammad Shahzad Shamim.

Multiple intraoperative aids have been introduced to improve the extent of resection (EOR) in Glioblastoma Multiforme (GBM) patients, avoiding any new neurological deficits. Intraoperative MRI (iMRI) has been debated for its utility and cost for nearly two decades in neurosurgical literature. Rev


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