|
|
|
|
 |
Original Articles |
|
A comparison of WHO guidelines issued in 1997 and 2009 for dengue fever — single centre experience
Munawar Khursheed,
Uzma Rahim Khan,
Kiran Ejaz,
Jabeen Fayyaz,
Irum Qamar,
Junaid Abdul Razzak,
Objective: To compare the original (1997) and revised (2009) versions of World Health Organization guidelines for dengue patients
Methods: Adult patients with a positive dengue Immunoglobulin M serology, and a diagnosis of dengue were included in the study at Aga Khan Univers....
|
|
Fingertip injuries in paediatric patients — experiences at an emergency centre in Saudi Arabia
Abdullah Foraih Al-Anazi,
Objectives: To investigate the etiological factors, intensity of injuries and the possible preventive measures of fingertip injuries and to avert such calamities.
Methods: A study was undertaken retrospectively on 200 children who had presented with fingertip injuries to the ....
|
|
Randomised controlled trial: Effects of aerobic exercise training programme on indices of adiposity and metabolic markers in hypertension
Sikiru Lamina,
Chuba Goddy Okoye,
Shmaila Mustapha Hanif,
Objective: To investigate the effects of interval training programme on blood pressure, maximal oxygen consumption, indices of adiposity and metabolic markers in black African men with essential hypertension.
Methods: The study was conducted at Murtala Muhammed Specialist Hos....
|
|
Association between chronic low back pain, anxiety and depression in patients at a tertiary care centre
Muhammad Amir Sagheer,
Muhammad Farhan Khan,
Salman Sharif,
Objective: To observe the prevalence of anxiety and depression in chronic low back pain population at a tertiary care centre.
Methods: The prospective cross-sectional study was conducted using convenience sampling at the Department of Neurosurgery, at Liaquat National Hospita....
|
|
Comparison of the TIMI and the GRACE risk scores with the extent of coronary artery disease in patients with non-ST-elevation acute coronary syndrome
Mazhar Mahmood,
Abdul Samad Achakzai,
Parveen Akhtar,
Khan Shah Zaman,
Objective: To compare the accuracy of the Global Registry of Acute Coronary Events risk score and the Thrombolysis In Myocardial Infarction risk score in predicting the extent of coronary artery disease in patients with non-ST segment elevation acute coronary syndrome.
Methods:
|
|
Morbidity from episiotomy
Aliya Islam,
Ayesha Hanif,
Ambreen Ehsan,
Saadia Arif,
Shaharyar Khan Niazi,
Asfandyar Khan Niazi,
Objective: To assess the morbidity from episiotomy.
Methods: The prospective randomised control study was conducted at the Military Hospital Rawalpindi\'s Gynaecology & Obstetrics Department from January 2006 to April 2008. It comprised 100 patients who were given a med....
|
|
Single centre study of using bendamustine in the treatment of B-cell malignancies
Asif Husain Osmani,
Nehal Masood,
Objective: To evaluate the experience of bendamustine in the treatment of B-cell malignancies at a tertiary care centre.
Methods: The retrospective descriptive analysis included data of all adult patients with B-cell malignancies treated with bendamustine from 2009 to 2011 at....
|
|
A one-year follow-up study of ocular and systemic complications of intravitreal injection of bevacizumab (Avastin)
Uzma Fasih,
Nisar Shaikh,
Atiya Rahman,
Sharjeel Sultan,
Mohammad Shafi Fehmi,
Arshad Shaikh,
Objectives: To report systemic and ocular complications within a year of intravitreal injection of bevacizumab (Avastin) in ocular neovascularisation.
Methods: The quasi-experimental (randomized without control) study was carried out at the Eye Department of Abbasi Shaheed Ho....
|
|
Pattern of illicit drug use in patients referred to addiction treatment centres in Birjand, Eastern Iran
Parissa Karrari,
Omid Mehrpour,
Reza Afshari,
Daniel Keyler,
Objective: To evaluate the pattern of use of opioid and other illegal drugs in patients seeking addiction treatment in Birjand, eastern Iran.
Methods: The prospective study was conducted from March 21, 2009 to March 21, 2010, and comprised all patients referred to the seven a....
|
|
Benzodiazepine use in medical out-patient clinics: a study from a developing country
Muhammad Junaid Patel,
Syed Ahmer,
Faheem Khan,
Abdullah Waqar Ahmed Qureshi,
Muhammad Farrukh Shehzad,
Sania Muzaffar,
Objective: To estimate the prevalence of Benzodiazepine use in the outpatient setting of general medicine clinics at a single tertiary care centre.
Methods: The prospective prevalence study was conducted in the outpatient setting of Internal Medicine Clinics at Aga Khan Unive....
|
|
Is vivax malaria really benign? — A Karachi-based study
Sabeen Aatif,
Qaisar Jamal,
Anila Altaf,
Salimullah,
Objective: To observe the disease pattern of vivax malaria, and to identify the various laboratory abnormalities associated with it.
Methods: The descriptive cross-sectional study was conducted at the Department of Medicine, Abbasi Shaheed Hospital, Karachi, from July to Sept....
|
|
FDG-PET scan in assessing lymphomas and the application of Deauville Criteria
Umm-e-Kalsoom Awan,
Neelam Siddiqui,
Mohammad SaadUllah,
Humayun Bashir,
Zia Salman Farooqui,
Narjis Muzaffar,
Mohammad Tariq Mahmmood,
Objective: To evaluate the role of Fluorine-18-fluorodexoyglucose Positron Emission Tomography (FDG-PET) scan in staging and its implications on the treatment of lymphoma, and to study the concordance between visual assessment and Deauville criteria for the interpretation of interim scans.....
|
|
Transradial primary percutaneous coronary intervention — experience from a tertiary care cardiac centre
Ayaz Hussain Shaikh,
Bashir Hanif,
Asad Pathan,
Shahrukh Hashmani,
Mohsin Raza,
Waqar Khan,
Syed Muhammad Faisal Hussain,
Syed Muhammad Saad Hussain,
Sumaira Nasir,
Objective: To determine the outcomes of primary percutaneous coronary intervention via transradial approach in a tertiary care cardiac centre.
Methods: The study retrospectively reviewed the medical records of 160 consecutive patients who presented to Tabba Heart Institute, a....
|
|
The effects of physical therapy on exaggerated muscle tonicity, balance and quality of life on hemiparetic patients due to stroke
Mohammad Reza Hoseinabadi,
Hamid Reza Taheri,
Fahimeh Keavanloo,
Mohammad Seyedahmadi,
Mehdi Mohamadinia,
Akbar Pejhan,
Objective: To determine the effects of physical therapy on balance, exaggerated muscle tonicity and quality of life on patients with hemiparesis.
Methods: This quasi-experimental study was conducted in 2011 among male hemiparetic patients secondary to stroke, at a physiothera....
|
|
A descriptive study to find possible correlation between MRI findings of pituitary gland and serum prolactin level
Muhammad Azeemuddin,
Rohana Naqi,
Mohammad Wasay,
Objective: To explore equation, if any, between findings of magnetic resonance imaging of pituitary gland and serum prolactin level.
Methods: The retrospective, descriptive study was conducted at the Department of Radiology, Aga Khan University Hospital, Karachi, and related ....
|
|
Comparison of pregnancy outcomes in women with sickle cell disease and trait
Shumaila Zia,
Muhammad Rafique,
Objective: To compare the pregnancy and neonatal outcome in sickle cell disease and trait women.
Method: The retrospective comparative study was conducted at Abha General Hospital, Abha, Saudi Arabia, from January 2009 to December 2011. The records of women having sickle cell....
|
|
Efficacy and safety of cinitapride in functional dyspepsia
Muhammad Tariq Baqai,
Mahmood Nasir Malik,
Faisal Ziauddin,
Objective: To study the efficacy and safety of cinitapride in the treatment of functional dyspepsia, and to evaluate the improvement of patients\' quality of life.
Methods: The prospective cross-sectional multi-centre phase IV study was conducted at Jinnah Hospital, Lahore,....
|
|
Comparison of surgical complications of intertrochanteric hip fractures between non-osteoporotic and osteoporotic patients
Masoud Shayesteh-Azar,
Mohamad Hossein Karimi-Nasab,
Majid Sajjadi-Saravi,
Seyed Mohamad Mehdi Daneshpoor,
Atefeh Hadian,
Golsa Olia,
Objective: To determine the role of bone quality in post-treatment complications among patients of intertrochanteric fracture.
Methods: The cross-sectional descriptive study was done on 61 patients who presented with intertrochanteric hip fractures to two affiliated hospitals....
|
|
Effects of baby-friendly hospital initiative on breast-feeding practices in Sindh
Mahjabeen Khan,
Durre Samin Akram,
Objective: To determine changes in the breastfeeding practices of mothers after receiving counseling on \'Ten Steps to Successful Breastfeeding\' as defined by the Baby Friendly Hospital Initiative comparing baby friendly hospitals (BFHs) and non-baby-friendly hospitals in Sindh, Pakis....
|
|
Surgical site infection following hernia repair in the day care setting of a developing country: a retrospective review
Amyn Pardhan,
Samia Mazahir,
Abdul Rehman Alvi,
Ghulam Murtaza,
Objective: To determine the incidence proportion of surgical site infection following hernia repair in a daycare setting at a tertiary care hospital of a low-income country.
Methods: The retrospective audit was done at the Aga Khan University Hospital, Karachi, from June 1, 2....
|
|
|
|
Review Articles |
|
Treatment of the depressive phase of bipolar affective disorder: a review
Ather Muneer,
Bipolar disorder is a chronic mood disorder which usually has its onset in adolescence and young adulthood. The disorder is typified by a remitting and relapsing course. While remissions are often partial in nature, relapses are frequent and manifested as manic, mixed, hypomanic and depressive ep....
|
|
|
|
Short Reports |
|
Prevalence of undifferentiated fever in adults of Rawalpindi having primary dengue fever
Humaira Zafar,
Abbas Hayyat,
Naeem Akhtar,
Syeda Fatima Rizwan,
The objectives of the study were to highlight early subclinical presentation of dengue viral infection (DVI) as an undifferentiated febrile illness. The descriptive cross-sectional study was carried out at Microbiology Department, Rawalpindi Medical College from March to September 2009. Stratifie....
|
|
|
|
Case Reports |
|
Total hip arthroplasty in a 6-month-old acetabulum fracture-dislocation of the hip: an 8-year follow-up
Kashif Mahmood Khan,
Anisuddin Bhatti,
Khurram Rasheed,
Old unreduced acetabulum fracture-dislocation is common in developing countries due to various factors. Different options including arthrodesis, Girdlestone arthroplasty and total hip replacement (THR) are used for its treatment. THR with reconstruction of the acetabulum is recommended, but not m....
|
|
Huge mesenteric liposarcoma
Mohammad Iqbal Khan,
Afsheen Zafar,
Maleeha Younas,
Irfan Malik,
Primary mesenteric liposarcoma is extremely rare and is treated by aggressive surgical management i.e. wide excision with adequate margins (in the absence of distant metastases). We report a case of huge slow-growing primary mesenteric liposarcoma in a 52-year-old man, who presented with gross ab....
|
|
Giant molluscum contagiosum in an immunocompetent child
Ayse Serap Karadag,
Remzi Karadag,
Serap Gunes Bilgili,
Omer Calka,
Yuhanize Tas Demircan,
Molluscum contagiosum is a skin disorder caused by DNA poxvirus and frequently seen in children. It is self-limited in immunocompetent hosts. It can present as numerous, treatment-resistant, atypical lesions in immunosuppressive patients and resistant to treatment. Atypical forms can rarely be se....
|
|
Histopathological features of an incidental case of cytomegalovirus salpingitis in a patient with inflammatory bowel disease
Wesal Al Rabih Fpathfu,
Yaqoob Nausheen,
Rabab Alottas Fpathkfu,
Ahmed Al Khudairi,
Dalal Nemenqani,
Ovarian and fallopian tube cytomegalovirus (CMV) infection is a rare finding, reported mostly in autopsy studies of immunocompromised patients. We report here a case of CMV salpingitis in a 22-year-old female, with Crohn\'s disease and on immunosuppressive drugs. The fallopian tube involvement ....
|
|
Endobronchial lipoma
Filiz Eren,
Tarik Candan,
Bulent Eren,
Nil Comunoglu,
Cem Comunoglu,
Endobronchial lipomas are rare benign tumours of the lung. The reported case was a 56-year-old man who visited the public hospital with complaints of chest pain and persistent cough. On bronchoscopy, a smooth-surfaced polypoid tumour obstructing the main bronchus in the left lobe was detected. Th....
|
|
A case of orf (ecthyma contagiosum) with multiple lesions
Enver Turan,
Yavuz Yesilova,
Derya Ucmak,
Orf, also known as ecthyma contagiosum or contagious pustular dermatitis, is a viral zoonotic disease resulting from the direct or indirect contact of damaged skin with infected animals. The causative microorganism is the orf virus, an epitheliotropic DNA virus from the Parapoxvirus group, which ....
|
|
|
|
Student's Corner |
|
HIV, Hepatitis B and Hepatitis C in garbage scavengers of Karachi
Mohammad Uzair Abdul Rauf,
Muhammad Danish Saleem,
Muhammad Osama Anwer,
Gulrays Ahmed,
Sina Aziz,
Muhammad Ashraf Memon,
Objectives: To determine the seroprevalence of human immunodeficiency virus, hepatitis B and C, and to study the associated risk factors in garbage scavengers of Karachi.
Methods: The cross-sectional study was performed in a colony inhabited by low socioeconomic garbage-colle....
|
|
Management of acute myocarditis in children
Quratulain Merchant,
Anwarul Haque,
Babar Sultan Hasan,
Myocarditis is defined as the inflammation of the myocardium. It continues to be a significant cause of morbidity and mortality in the paediatric population and is the commonest cause of cardiac failure in a healthy child. Some studies estimate the incidence of myocarditis to be around 1 per 100 ....
|
|
Robotic cardiothoracic surgery in Pakistan: A novel minimally invasive form of patient care
Syed Hassan Abbas Naqvi,
Asfandyar Sheikh,
Syed Hassan Shiraz Naqvi,
Kainat Sheikh,
Madam, cardiovascular disorders are the leading cause of death worldwide. Technological advances have led to a marked reduction in the morbidity and mortality of cardiac patients. Novel techniques, which involve the use of robotics, have revolutionised the field of cardiac surgery, by increasing ....
|
|
The effect of left atrium volume on patients’ prognosis in acute myocardial infarction
Mohamad Goldust,
Rezvanie Salehi,
Jahanbakhsh Samadikhah,
Rasul Azarfarin,
Madam, diastolic function evaluated following acute myocardial infarction using Doppler echocardiography provides important prognostic information.1,2 Evaluating left atrium volume is a good way to estimate prognosis in patients with acute myocardial infarction as it indica....
|
|
|
|
Letter to the Editor |
|
Does coconut oil reduce the risk of coronary artery diseases?
Ailya Inayat,
Shoukat Ali Baig,
Tooba Baqai,
Madam, being a consequence of atherosclerosis, which itself is a progressive disease caused by the build-up of fatty plaques in the heart vessels, coronary artery disease (CAD) figures prominently as public health problem and it is unsurprising that it is now the leading cause of death worldwide.....
|
|
|
|
Evidence Based Medicine |
|
Benefit of neuroprotection in acute ischaemic stroke, shall we dare to hope?
Anjum Akhtar,
Ayeesha Kamran Kamal,
Calcium influx is the final pathway of death in hypoxia. Numerous randomized clinical trials have been conducted to assess the effect of calcium channel blockade for neuroprotection in acute ischaemic stroke but the majority of them failed to show any benefit.
What is the study under co....
|
|
|
|
Learning Research |
|
Presenting budget in a research grant application
Junaid Ahmed Bhatti,
Umbreen Akhtar,
Bilal Arshed Butt,
Naveed Zafar Janjua,
An innovative research idea does not mean a successful grant application.1,2 Convincing details about the feasibility and the team are important grant winning combinations in a competitive grant review.3 Once reviewers have understood the research pro....
|
|
|
|
Recent Advances In Endocrinology |
|
Diabetes and dyslipidaemia
Sanjay Kalra,
Ambika G Unnikrishnan,
Diabetes and dyslipidaemia are two common comorbid conditions encountered in clinical practice. This review discusses the screening, investigations, non-pharmacological and pharmacological management of dyslipidaemia in type 2, type 1, and pre-diabetes, with a view to improving cardiovascular out....
|
|
|
|
|
|
 |
News & Events |
|
|
|
|
 |
Index |
|
|
|
Supplement |
|
|
|
|
Issue Vol:63, No:6 June, 2013
