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March, 2001 >>

Anatomical Variations of Internal Jugular Vein as seen by ďSite Rite IIĒ Ultrasound Machine - an initial experience in Pakistani Population

Hameedullah, M. A. Rauf, F. H. Khan  ( Department of Anaesthesia. The Aga Khan University Hospital, Karachi. )

Abstract

Objective: To determine the anatomical variations of the internal jugular vein (IJV) in Pakistani adult population with the help of Site Rite II ultrasound machine.
Material and Method: The right IJV relation to the carotid artery was visualized at four different landmarks (angle of the mandible, thyroid cartilage, cricoid cartilage, and the supraclavicular area). Size of IJV in comparison to carotid artery was also seen.
Results: In 49 cases the IJV was found in aberrant relation to carotid artery at the angle of the mandible (p value <0.05), 22 at the thyroid cartilage, 20 at the cricoid cartilage, and 46 at the supraclavicular area (p value <0.05). In 93% of cases the IJV was found to be larger than the carotid artery.
Conclusion: Care should be taken while cannulating IJV at the angle of the mandible and supra clavicular area by external landmark guided technique. Ultrasound guided technique should be used in every anticipated difficult case (JPMA 51:105:2001).


Introduction

Central venous cannulation is a commonly performed procedure by the anaesthesiologists in the operating room and intensive care unit for various reasons like massive volume resuscitation, administration of vasopressor agents, monitoring central haemodynam Ic parameters, tern porary transvenous pacemaker insertion, infusion of irritant solutions and administration of total parental nutrition1.
It can be inserted through various sites like the antecubital veins, subclavian vein, internal jugular vein, external jugular vein and femoral vein. The right internal jugular vein (IJV) is a commonly used route for access to
central circulation by most anaesthesiologists because of its consistent anatomical position, easy accessibility during surgery, direct route into the right atrium, large diameter during trendelenberg position, predictable location and minimal likelihood for obstruction along its route to the right atrium2. It can also be reached faster than the subclavian vein3. The standard approach to right lJV cannulation uses visual and palpable anatomic landmarks to guide needle placement and is associated with a 95% success rate4. However various types of complications have been reported, even with internal jugular vein cannulation, including failure to locate the vein, cawtid artery puncture, puncture of the stellete ganglion, vagal nerve pulmonary artery, vertebral artery, aorta, mediastinurn and pleura5.
Ultrasound may be used to give images of both the carotid artery and internal jugular vein in the neck6. There are a variety of ultrasound machines available but they tend to be large, complicated, expensive and not readily available. A new device, the ‚ÄúSite Rite-Il‚ÄĚ (Dymax) is a portable, light weight, real time ultrasound imaging system especially designed for viewing the internal jugular vein and carotid artery. It gives images similar to the large ultrasound machines and when used aseptically during cannulation, direct visualization of the position and direction of the locating needle can aid internal jugular vein location7.
Although the ultrasound method has compared favorably with the landmark technique, its widespread use has been hampered by the impracticality and expense of full sized echo devices and by the absence of larger prospective study data8.
The anatomical position of the IJV is generally lateral and anterior to the carotid artery9,10. An anatomical position of the internal jugular unreliability of the external landmarks may underlying cause of difficult access or damage to structures11. Thus the objective of this study was to determine the anatomical variations of the internal jugular vein, if any, in the adult Pakistani population with the help of Site Rite II ultrasound machine.


Materials and Methods

After approval from the Human Subject Protection Committee of The Aga Khan University Hospital, a descriptive, observational and cross sectional study was started in the operating rooms of the university. Two hundred subjects were randomly selected which included patients coming for elective surgeries, doctors and paramedical staff working in the operating rooms, on the basis of convenient sampling. Subjects were of either sex aged greater than 16 years. Subjects with history of any previous surgery on the neck, neurosurgical cases, those having swelling or mass in the neck, younger than 16 years and who refused the procedure were excluded from the study.
Technique of Procedure
Verbal consent was taken from every individual entering the study before performing the procedure. Right side of the neck was selected as the study site for internal jugular vein examination. All the patients were made to lie supine without a pillow on the operating table with their head maximally rotated to the leftU. The relationship of the internal jugular vein to the carotid artery was recorded at the angle of mandible, at the level of thyroid cartilage, cricoid cartilage and 2 cnis. above the clavicle and, the sizes of the vein and to the artery were compared.
Statistical Analysis
The data was analyzed on Epi-info 6.02 software package. The differences between the established documented anatomy of internal jugular vein in International text books9,10 and this study sample were determined by applying Chi square test of independence. Five percent of flexibility was allowed and p value <0.05 was considered statistically significant.


Results

Total number of cases studied were 200. The demographic data of these subjects is shown in Table 1.

The relationship of internal jugular vein with that of carotid artery was studied at four different sites and the following differences were noted:
1. Angle of the Mandible
At the angle of mandible. the IJV was not visible in 19 cases. One hundred thirty two cases (66%) had normal relation of IJV with carotid artery (antero-lateral and lateral), while in 5 cases it was anteromedial, in 40 cases anterior, in 2 postero-lateral and I each posteromedial and medial to the artery. The results showed a 14.56 degree of freedom with p value <0.05 (Table 2).



2. Thyroid Cartilage
At this site 178 cases (89%) had normal anatomy of IJV in relation with carotid artery (antero-lateral and lateral). Twenty two cases showed abnormal placement of these 5 were antero-medial 16 anterior and I was postero­medial. The results showed a 2.45 degree of freedom with non-significant p value (Table 2).
3. The Cricoid Cartilage
One hundred eighty cases (90%) had normal relation i.e. anterolateral and lateral. In 2 cases the internal jugular vein was anteromedial to the artery, in 1 7 anterior and in 1 it was posteromedial. The Chi square test with 5% flexibility came out to be 1.80 degree of freedom and p value was statistically non-significant (Table 2).
4. At Supraclavicular Area
At this landmark, the internal jugular vein or carotid artery were visulized in 2 cases. In 4 cases the vein was antero-medial to the artery, in 3 1 anterior, in 121 antero­lateral, in 41 lateral and in 1 case it was posterolateral. At this point anterior and anterolateral was considered as the normal in 152 cases (76%). By applying Chi square test of independence and considering 5% as flexibility the result was 14.56 degree of freedom and p value was <0.05 that is statistically highly significant (Table 2).
Size of Internal Jugular vein to Carotid Artery
Of the 200 cases the internal jugular vein was larger than the carotid artery throughout the course in 186 cases, which was expected and considered normal. In 12 cases the vein was equal and in 2 it was smaller than the artery. By applying the Chi square test with 5% flexibility the p value was non-significant.


Discussion

Central venous cannulation is now becoming a standard procedure in many patients for various reasons1. Different sites for central venous access have been used but the internal jugular vein is the most popular site among anaesthetists because of its consistent anatomical position, large diameter in Trendelenberg position, easy accessibility intraoperatively and minimal likelihood of obstruction along its route to the right atrium12.
Internal jugular vein cannulation is commonly performed using external anatomical landmarks13. The physicians with little experience tend to have a higher complication rate during IJV cannulation14. Injury to one of the adjacent arteries is a major complication of which the most common is carotid artery puncture15. To decrease the complication rate accurate knowledge of the location of internal jugular vein is important for its cannulatio14.
The anatomical position of IJV is generally lateral, anterior and/or anterolateral to the carotid artery and variation in relative position of these vessels can complicate the IJV cannulation12. To prevent this, Doppler and (2-D) two-dimensional ultrasound have been developed as technical aids to assist central venous catheterization through the IJV route. The ‚ÄėSite Rite II‚Äô 2-D ultrasound machine (Dymax Corporation, Pittsburg, PA) was used in this study for imaging the relative anatomy of IJV. The superiority of this technique compared with landmark guided cannulation is that the machine is simple to use with minimal technical problems. It improves the subjective ease of cannulation, reduces the number of attempts required to locate the internal jugular vein, shortens the procedure time, and lessens the complication rate7.
The hypothesis that an aberrant anatomical position of the internal vein or unreliability of the external landmarks may be associated with racial and geographical variation of IJV was assessed in this study. The static anatomic features of IJV with carotid artery at the angle of the mandible, thyroid cartilage, cricoid cartilage and supra-clavicular area were evaluated. At these points the relation of the internal jugular vein to carotid artery, as well as their size relations were recorded.
Based on the ultrasound findings the relation of the IJV to the carotid artery at the angle of the mandible was found to be normal i.e. anterolateral and lateral in 66% cases. In 9.5% of cases the vein was not visible on ultrasound at this location which was the most dramatic aberrancy. This could be because of many reasons including observer bias, congenitally absent vein on right side, anatomical variation and thrombosis or occlusion due to previous cannulation8. There are two other possible explanations for this non-visualization. Firstly, the ultrasound scanner could not identify the IJV because the diameter of vein was so small and secondly, the ultrasound probe occluded the vein by excessive pressure of the probe on the neck vasculature. Twenty percent of IJVs were directly anterior to the carotid artery, 2.5% were anteromedial, 1 .0% posterolateral and 0.5% were medial and posteromedial each. So in 24.5% of cases the anatomy of the IJV was sufficiently aberrant to complicate access by a blind method.
At the thyroid and cricoid cartilage, the incidence of normal relation with carotid artery was 89% and 90% respectively. Here the IJV was positioned in intimate contact, laterally and anterolaterally to the carotid artery. Thus statistically insignificant number of patients had an aberrant anatomy of IJV at these locations.
Finally at the supra ciavicular area the IJV was found at its expected position i.e. anterior and anterolateral in 76% of cases, leaving 24% in abnormal locations. At this site also the cannulation would lead to complications if only external landmark technique is used.
The results of this study are comparable with the ultrasound based study by Armstrong et al, which demonstrated variation in size and anatomic relationship of the carotid artery to the IJV. it revealed that 5.0% of IJVs were lying at abnormal location at the level of the cricoid cartilage7.
Another study examined anatomic variations of IJV using an ultrasound device in 200 adult patients11. They found that in 8.0% of patients, the position of the IJV did not correspond well to that expected from standard surface landmarks. In 3.0% patients the IJV was unusually small and did not increas in diameter during the Valsalva maneuver.
Alderson et al. showed the IJv anatomy in the paediatric age group16. They found that in 82.0% of patients the IJV ran anterolaterally to the carotid artery while in 4.0% of patients the vein was in a similar position relative to the carotid artery. but was of unusually small diameter. In 10.0% the vein ran medially, in 2.0% it ran widely lateral to the carotid artery.
Lin and Kong et al. studied 104 uraernic patients with the help of’Site Rite and observed the IJV anatomy on both sides. They found the anatomical variation on right IJV in 19 cases (18.3%) and left IJV in 17 cases (16.4%). This might contribute to difficulty in external landmark guided IJV cannulation17.
it is concluded that there are anatomical variations of internal jugular vein in Pakistani population. The angle of the mandible and supraclavicular area are the landmarks where statistically significant (p value <0.05) anatomical variations of IJV are found. So while cannulating IJV with external landmark guided technique, one should avoid these landmarks and use either the thyroid cartilage or cricoid cartilage as landmarks. In cases where anatomical landmarks are not clear or distorted and there is expected difficult cannulation, the ultrasound device, ‚ÄėSite Rite‚Äô should always be used. Patients who cannot be cannulated by using anatomical landmarks alone may be successfully cannulated by ultrasound guidance.


References

1.Mallory DL. McGee WI, Shawker TH, et al. Ultrasound guidance improves the success rate of internal jugular vein cannulation. A prospective, randomized trial. Ches, 1990: 98:157.60.
2.Sanford TJJ. Internal jugular vein cannulation versus subclavian vein cannulation. An anesthesiologist’s view: the right internal jugular vein. J.Clin.Monit.. 1985;1 :58-61.
3.Senagorc A, Walter JD, Bonnell BW. et al. Pulmonary artery cathetenzation: a prospective study of internal jugular and subclavian approaches Crit.Care Med. 1987;15:35-37.
4.Jobes DR. Schwartz AJ, Greenhow DE, et al. Safer jugular vein cannulation: recognition of arterial puncture and preferential use of the external jugular route. Anesthesiology 1983,59:353-55.
5.Gamulin Z, Bruckner JC, Forster A, et at. Multiple complications after internal jugular vein catheterisation. Anaesthesia 1986.41:408-12.
6.Metz S. Horrow JC, Balcar 1 A controlled comparison of techniques for locating the internal jugular vein using ultrasonography. Anesth.Analg. 1984:63:673-79.
7.Armstrong PJ, Cullen M, Scott DH. The ‚ÄėSiteRite‚Äô ultrasound machine--an aid to internal jugular vein cannulation. Anaesthesia, 1993:48:319-23.
8.Denys BG, Uretsky BF, Reddy PS. Ultrasound-assisted cannulation of the internal jugular vein, A prospective comparison to the external landmark-guided technique. Circulation, 1993:87: 1557-62.
9.Angiology. In: Williams PL, Warwick R, Dyson M, et al. eds. Grav's Anatomy. Edinburgh, Churchill Livingstone. 1989 .pp.662-858.
10.Head and Neck, Suprahyoid region. In: McMinn RMH, Last RJ, eds. Last’s Anatomy, Regional and Applied. Edinburgh, Churchill Livingstone, 2000:pp.421-578.
11.Denys BG, Uretsky BE Anatomical variations of internal jugular vein location: impact on central venous access. CritCare Med., 1991:19:1516-19.
12.Sulek CA, Gravenstein N, Blackshear RH, et al. Head rotation during internal jugular vein cannulation and the risk of carotid artery puncture. Anesth.Analg., l996;82: 125-28.
13.English IC, Frew RM. Pigoti JF, et al . Percutaneous cannulation of the internal jugular vein. Thorax. I 969;24:496-97.
14.Koski EM, Suhonen M. Mattila MA. Ultrasound-facilitated central venous cannulation, Crit.Care Med., 1992:20:424-26.
15.Eckhardt WF Inadvertent carotid artery cannulation during pulmonary artery catheter insertion. J. Cardiothoracic Vascular Anesth., 1996;1O:283-90.
16.Alderson PJ, Burrows FA, Stemp LI, et al. Use of ultrasound to evaluate internal jugular vein anatomy and to facilitate central venous cannulation in paediatric patients. Br.J.Anaesth. I 993;70: 145-48.
17.Lin BS, Kong CW, Tarng DC, et al. Anatomical variation of the iuternal jugular vein and its impact on temporary haemodialysis vascular access: an uItrasonographic survey in uraemic patients. Nephrol. Dial Transplant., 1998:13:134-38.


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