|
 |
Editorial |
|
Thrombotic Microangiopathies: Role of ADAMTS-13
Salman Naseem Adil,
Farheen Karim,
Thrombotic microangiopathy (TMA) refers to conditions that cause microvascular thrombosis and result in microangiopathic haemolytic anaemia with presence of fragmented red cells on peripheral blood, thrombocytopenia and end organ damage. Syndromes most commonly associated with thrombotic microang....
|
|
|
|
Original Articles |
|
Uveitis is not just an ophthalmologists’ concern
Muhammad Ishaq,
Jibran Sualeh Muhammad,
Khalid Mahmood,
Objective: To find the causes and characteristics of uveitis and its subtypes among Pakistani population, and to create awareness that early diagnosis and treatment of uveitis requires a multi-disciplinary approach.
Methods: The retrospective study involved 98 diagnosed uveit....
|
|
Endoscopic Retrograde Cholangiopancreatography: A therapeutic modality in children and adolescents
Muhammed Ali Taj,
Aftab Leghari,
Sajida Qureshi,
Shahriyar Ghazanfar,
Saad Khalid Niaz,
Muhammed Saeed Quraishy,
Objective: To evaluate the indications, clinical features, complications, and effect on patient management of Endoscopic retrograde cholangiopancreatography (ERCP) in paediatric patients of varying age.
Methods: A prospective, descriptive cross sectional study was conducted a....
|
|
The effect of an anaphylaxis guideline presentation on the knowledge level of residents
Rabia Kahveci,
Ilknur Bostanci,
Yildiz Dallar,
Objective: To determine the effects of an anaphylaxis guideline presentation in residency training, which is an important period for having skilled and knowledgable doctors in the future and see how the residents' level of knowledge changes after presentation. The study is the first in Tu....
|
|
An institutional review of transarterial embolization in haemorrhagic urological emergencies
Raza Sayani,
Muhammad Azeemuddin,
Tanveer ul Haq,
Rana Shoaib Hamid,
Basit Salam,
Objective: To review the effectiveness of therapeutic transarterial embolization in controlling phagic urological emergencies irrespective of the cause of emergencies.
Methods: Thirty-seven vascular angiographies were performed in 32 patients (19 males and 13 females, age ran....
|
|
NOTES: ‘pre-dilatation’ as a remedy for technical issues during transgastric access
Qurratulain Hyder,
Wen Li,
Ziuli Zhang,
Yunsheng Yang,
Xiaochuan Liu,
Objective: To identify and resolve procedural issues during transgastric access for the Natural Orifice Translumenal Endoscopic Surgery (NOTES), where feasibility and safety is established in animals and humans. However, several technical problems during viscerotomy result in considerable ....
|
|
Perception of tuberculosis in Pakistan: findings of a nation-wide survey
Sara Ijaz Gilani,
Muhammad Khurram,
Objective: To assess knowledge about symptoms, diagnosis, treatment, transmission, and impact of tuberculosis in Pakistan.
Methods: This nationwide survey was carried out by face to face interviews with 2742 men and women from December 2009 to June 2010. Multiple stage random....
|
|
Breast cancer risk factors: A comparison between pre-menopausal and post-menopausal women
Zeeshan Butt,
Syed Furqan Haider,
Shumaila Arif,
Muhammad Raza Khan,
Umair Ashfaq,
Umer Shahbaz,
Mulazam Hussain Bukhari,
Objective: To evaluate the difference between pre- and post-menopausal breast cancer regarding menstrual and reproductive risk factors
Methods: The case-control study was conducted in Mayo Hospital, Lahore, between October 2008 and April 2009. Cases were breast cancer patient....
|
|
Acute myeloid leukaemia in children: Experience at a tertiary care facility of Pakistan
Zehra Fadoo,
Naureen Mushtaq,
Saima Alvi,
Muhammad Ali,
Objective: To document the demographics and outcome of children with Acute Myeloid Leukemia (AML) treated at a tertiary care facility of Pakistan.
Methods: A retrospective study was conducted at Aga Khan University on children (less than 15 years) diagnosed to have AML betwee....
|
|
Characteristics of acute adult poisonings in a university hospital emergency department in central Turkey: a three-year analysis
Levent Avsarogullari,
Vesile Senol,
Okhan Akdur,
Aynur Akin,
Polat Durukan,
Seda Ozkan,
Objective: To evaluate the etiologic and demographic characteristics of acute adult poisoning cases and to obtain up-to-date information on acute poisonings.
Methods: A retrospective study was conducted to evaluate 1254 adults who presented with acute poisoning to the E....
|
|
Correlation of divalent Cat Ions (Ca++, Mg++) and Serum Renin in pateints of essential hypertension
Inayat-ur-Rahman Abbasi,
Salim-ul-Haque,
Muhammad Wasim Kausar,
Khemomal A. Karira,
Nudrat Anwar Zubari,
Objective: To evaluate the serum status of Divalent Cat ions (Ca++ and Mg++) in hypertensive subjects along with correlation of Cat ions with serum Renin in all subjects.
Methods: Conducted at the Biochemistry Department of the Basic Medical Sciences Institute (BMSI), Jinnah ....
|
|
Ocular injuries in blast victims
Mumtaz Alam,
Mustafa Iqbal,
Akbar Khan,
Sher Akbar Khan,
Objective: To study the type and severity of ocular injuries in blast victims.
Methods: It was a descriptive case series. The study was conducted at the Department of Ophthalmology, Khyber Teaching Hospital and Iqbal Eye Clinic Peshawar from March 2010 to May 2011. Detailed h....
|
|
Analysis of One-Best MCQs: the Difficulty Index, Discrimination Index and Distractor Efficiency
Mozaffer Rahim Hingorjo,
Farhan Jaleel,
Objective: To investigate the relationship of items having good difficulty and discrimination indices with their distractor efficiency to find how 'ideal questions' can be affected by non-functioning distractors (NF-Ds).
Methods: The cross-sectional study was conducted at F....
|
|
|
|
Review Articles |
|
Sedation for children undergoing cardiac catheterization: A review of literature
Syed Muhammad Abbas,
Abdul Rashid,
Hammad Latif,
Management of children with congenital heart disease has been a great challenge for anaesthesiologists especially during cardiac catheterization. General anaesthesia with positive pressure ventilation can alter the intra-cardiac pressures as well as shunt fraction. Therefore deep sedation with pa....
|
|
|
|
Short Reports |
|
Survey of sharp waste disposal system in clinics of New Karachi
Seher Qaiser,
The World Health Organization (WHO) estimates that there are 350 million people with chronic HBV infection and 170 million people with chronic HCV infection worldwide. Hepatitis B is estimated to result in 563, 000 deaths and hepatitis C in 366, 000 deaths annually. Given its large population (18....
|
|
|
|
Case Reports |
|
Asymptomatic presentation of giant bulla of the left apical and anterior segment of the left upper lobe of the lung with near complete atelectasis of the remaining left lung
Saulat Hasnain Fatimi,
Mahrukh Riaz,
Hashim Muhammad Hanif,
Marium Muzaffar,
Giant bullae may be found in association with emphysema. They present as pockets of entrapped air which grow as the surrounding lung retracts away. As they do not take part in gas exchange and merely occupy space, their presence leads to severe impediment of mechanical ventilation in the adjacent....
|
|
Laryngeal Tuberculosis presenting as Laryngeal Carcinoma
Anwar Suhail,
Muhammad Sheharyar Ahmed,
Zain-ul-Abdeen Sobani,
Shahzad Ghaffar,
Tuberculosis (TB) accounts for the highest number of mortalities among infectious diseases worldwide. Laryngeal TB is an extremely rare presentation of TB. It has many similarities to laryngeal carcinoma, one of the three most common cancers among males in the city, with an age standardized rate ....
|
|
Solitary metastasis of breast carcinoma in the infundibulum
Rohana Naqi,
Muhammad Azeemuddin,
We present a rare case of a 59 years old women who had been treated for breast cancer. Post Contrast T1-weighted MR images revealed a tiny nodular enhancing lesion in the infundibulum, consistent with metastasis.
Keywords: Breast carcinoma, Metastasis, Infundibulum. ....
|
|
Isolated tubercular liver abscess in an elderly diabetic successfully treated with systemic antitubercular drugs
Rahul Rai,
Vishwa Deepak Tripathi,
Vikas Rangare,
D. Sunil Reddy,
Pushpraj Patel,
Tubercular liver abscess is a rare extrapulmonary manifestation of tuberculosis. We are presenting a case of isolated tubercular liver abscess in a 70 year old diabetic male without any evidence of tuberculosis in the lungs or abdomen. Diagnosis was made on the basis of radiological findings alon....
|
|
Adult laryngeal haemangioma; a rare entity
Shabbir Akhtar,
Adeel Ahmed Shamim,
Shehzad Ghaffar,
Muhammad Sheryar Ahmed,
Mubasher Ikram,
Laryngeal haemangioma is commonly seen in children. Adult laryngeal haemangiomas are rare and usually involve the supraglottic region. Most common symptom includes dysphagia, dysphonia and shortness of breath. Detailed history, fiberoptic laryngoscopy and computerized scanning may suggest benign ....
|
|
Pleomorphic Xanthoastrocytoma: An Atypical Astrocytoma
Mubashira Hashmi,
Asad Abbas Jaffari,
Shaista Anwar Siddiqi,
Liaqaut Ali,
Naveen Faridi,
Junaid Ashraf,
Syed Ahmed Asif,
Pleomorphic xanthoastrocytoma (PXA) is rare primary neoplasm of brain. Despite its pleomorphic appearance, it has a relatively good prognosis. We report a case of biopsy proven pleomorphic xanthoastrocytoma in a young male who presented with visual and sensory symptoms, classical neuroimaging....
|
|
|
|
Opinion and Debate |
|
Vitamin D: Does it play a role in psychiatry?
Mukesh Mohan Bhimani,
Some People may be surprised to see a psychiatrist writing about a bone vitamin, but with recent advances in biomedical science and research, a number of non-skeletal diseases including major mental illnesses have been found, to be associated with Vitamin D deficiency.
Since its discovery ....
|
|
|
|
Student's Corner |
|
Cross-sectional study identifying forms of tobacco used by Shisha smokers in Pakistan
Sameer-ur-Rehman,
Mohammed Ali Sadiq,
Maria Adnan Parekh,
Ali Bin Sarwar Zubairi,
Philippe M. Frossard,
Javaid Ahmed Khan,
Objectives: To estimate the frequency of different forms of tobacco intake such as smoker's tobacco, chewable tobacco and snuff tobacco among shisha smoker's and to study the patterns and predictors of shisha smoking affecting youth from different cities of Pakistan.
Methods: <....
|
|
Transient osteoporosis of the hip
Rabeea Mirza,
Saliha Ishaq,
Hira Amjad,
Transient Osteoporosis of Hip (TOH) is an uncommon disorder of idiopathic nature, particularly in the Asian population. It has been described to mostly occur in middle aged men and women in their third trimester of pregnancy. A distinctive hallmark of this condition is that it is self limiting an....
|
|
|
|
Letter to the Editor |
|
Dilemma of indiscriminate use of Vena Cava filters
Madam, mechanical interruption of blood flow by femoral vein ligation as a means to protect against pulmonary embolism (P.E.) was first performed by John Hunter in 1784.1,2 Mobin-Uddin a Pakistani Vascular Surgeon was the first to introduce intra-luminal device in 1967.3 How....
|
|
Nutrition transition in Pakistan
Madam, South Asia today is at crossroads. More than half (55 percent including injuries) of the disease burden is now attributable to non-communicable or chronic diseases like heart disease, stroke, type 2 diabetes and cancers that is more than communicable diseases (infections), maternal and chi....
|
|
Going beyond the resident duty hours in Pakistan
Madam, we have read" Resident duty hours: Globally accepted standards and the situation in Pakistan" by Juma and Hosein1 with interest. We think that they have highlighted an important problem which is usually brushed under the carpets as it doesn't affect the senior faculty....
|
|
Ambulance Service: A call unheard
Madam, I am writing in reference to the Editorial titled "Role of pre-hospital care and ambulance services in Karachi" published Dec, 2011. The author presents a well-balanced argument in regards to the role of ambulance and Emergency Medical Services (EMS) in a city densely populated a....
|
|
|
|
Case Series |
|
Portal biliopathy
Muhammad Shahbaz Alam,
Qazi Saad Bin Khalid,
Muhammad Zeeshan,
Zishan Haider,
Portal biliopathy (PB) is a rare disorder, which mostly presents as sub-clinically. It occurs most commonly due to idiopathic extrahepatic portal vein obstruction. We present three cases having features of portal biliopathy secondary to portal hypertension. Our first case did not have a prior his....
|
|
|
|
Evidence Based Medicine |
|
My Patient has an elevated hs-CRP. What does this mean? What should I do now?
Maria Khan,
Emmon Raza,
Ayeesha Kamran Kamal,
Why is this trial important?
Hyperlipidaemia is an established risk factor for cardiovascular and cerebrovascular disease. A standard investigation to assess a person's hyperlipidaemia is the lipid profile. This measures total cholesterol, high density lipoproteins (HDL), low densi....
|
|
|
|
Audit Report |
|
Pattern of cases and its management in a general surgery unit of a rural teaching institution
Muhammad Shamim,
Shumaila Bano,
Syed Abdullah Iqbal,
Objective: To study the pattern of general surgery cases and their management in a rural teaching institution.
Methods: This descriptive case-series was conducted prospectively in Surgical Unit II at Fatima Hospital and Baqai Medical University, from June 16, 2005 to June 15,....
|
|
Clinical audit of emergency unit before and after establishment of the emergency medicine department
Afshin Amini,
Payam Dindoost,
Mehrdad Moghimi,
Hamid Kariman,
Ali Shahrami,
Hossein Ali-Mohammadi,
Mostafa Alavai-Moghaddam,
Hojjat Derakhshanfar,
HamidReza HatamAbadi,
Kamran Heidari,
Shahram Alamdari,
Mohammad Kalantar Meibodi,
Majid Shojaee,
Mohammad Mehdi Foroozanfar,
Behrooz Hashemi,
Anita Sabzeghaba,
Ali Kabir,
Objective: To assess the deficiencies and potential areas through a medical audit of the emergency departments, in six general hospitals affiliated to Shahid Beheshti University of Medical Sciences at Tehran, Iran, after preparing specific wards-based international standards.
Met....
|
|
|
|
Learning Research |
|
Selecting a research topic
Junaid A Bhatti,
Umbreen Akhtar,
Syed Ahsan Raza,
Kiran Ejaz,
We, the medical students, interns, residents, faculty, physicians and the health professionals are obligated to carry out research as a part of our medical training.1 The current medical knowledge which we can define as curriculum per se is based on continuous process of 'evidence acc....
|
|
|
|
|
|
 |
News & Events |
|
|
|
|
 |
Index |
|
|
|
Supplement |
|
|
|
|
Issue Vol:62, No:2 February, 2012