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Rotational Mal-Alignment after Reamed Intramedullary Nailing for tibial shaft fracture

Sher Baz Khan,Yasir Mohib,Rizwan Haroon Rashid,Haroonur Rashid  ( Orthopedics, Aga Khan University Hospital, Karachi. )

October, 2016


Intra-medullary (IM) nailing is standard of care for unstable tibial shaft fractures. Malrotation is very common but it is under-recognised, inpart because of variation in normal anatomy and partly due to difficulty in accurately assessing rotation. This study was planned to evaluate the frequency of rotational mal-alignment after reamed tibia IMnailing. This cross-sectional study was conducted at Aga khan University Hospital, Karachi, and comprised patients with tibia shaft fractures managed with IMnailing from January to December 2014. All the patients were assessed intra-operatively for rotational alignment using the knee and ankle fluoroscopic images. There were 81 patients with a mean age of 38±16.9 years. There were 64(79%) male patients. Overall the incidence of malrotation was in 20(24.7%) cases. Rotational mal-alignment is one of the preventable complications after IMnailing which can be assesed intra-operatively under fluoroscope.
Keywords: Tibialshaft fracture, Nailing, Malrotation, Rotational mal-alignment.



Tibialdiaphyseal fractures are the most common long-bone fractures. The goal of treatment in these cases is to attain rapid union with acceptable axial and rotational alignment while preserving the initial bone length. Several studies have shown that tibial nailing is associated with superior outcomes and less complication compared to those obtained with open reduction and internal fixation (ORIF), external fixation, or non-operative treatment in case of closed stable or unstable fractures.1

Tibial torsion is the anatomical twist of the proximal versus distal articular axis of the tibial bone in the transverse plane around the longitudinal axis. Any change in the tibial torsion, either in the internal or in the external direction, is considered a mal-rotation and can be seen after fixation of the tibial shaft fractures by closed intra-medullary (IM) nailing.

In many studies, tibialmalrotation has been measured clinically and the incidence is reported to be 0-6%; whereas such incidence is reported to be 22-36% by using other measurement methods such as computerised tomography (CT) scanning.2 One study found an incidence of 30% of rotational mal-alignment.3

The current study was planned to evaluate the frequency of rotational mal-alignment after reamed IMnailing of tibia.


Methods and Results

This cross-sectional study was conducted at Aga Khan University Hospital, Karachi, from January 1 to December 31, 2014. The sample size was calculated using the World Health Organisation (WHO) sample size calculator. Confidence level (1-a %) was taken as 95%, with precision (d) of 0.1. Taking the frequency of mal-alignment from literature as 30%,3 the sample size was calculated. Considering the largest sample size that was calculated for the frequency of mal-alignment, we achieved a sample size of 81. All patients between aged 15-80 years presenting to the emergency room (ER) or outpatient department (OPD) with traumatic tibial shaft fractures planned for closed IMnailing of tibia by a single consultant orthopaedic surgeon were included. Patients with pathological fracture, comminuted fracture requiring additional stability, non-unions, fractures reduced by open method, fractures extending to knee and ankle joints were excluded. All the patients were assessed intra-operatively for rotational alignment using the fluoroscopic images of knee and ankle of the same limb, as described in literature.4 First, a true lateral of the knee was obtained by superimposing the medial and lateral femoral condyles. With the leg held stationary, the fluoroscopic unit was rotated 90 degrees, which provided a true anterio-posterior (AP) view. If the tibial fracture was accurately reduced, rotation of an additional 10 to 15 degrees provided an accurate mortise view of the ankle. If it was more than 15 degrees, it was taken as external malrotation and if it was less than 10 degrees, it was declared internal malrotation (Figure)

SPSS 19 was used for data analysis. Mean ± standard deviation (SD)were computed for continuous variables i.e., age, and as frequency and percentage for nominal variables i.e., gender, site, side type of fracture and proportion of malrotation. Stratification with respect to age, gender site of fracture, type of fracture and associated fibular fracture was done to see the effect of these on outcome variable through chi square test. P<0.05 was considered significant.

Of the 81 patients, 64(79%) were male. The overall mean age was 38±16.9 years (range: 17 -80 years). Of the total, 31(38%) patients had fracture in the upper half of tibia, while in 50(62%) cases lower half of tibia was involved. Besides, 52(64.2%) patients had simple fractures, 11(13.6%) had wedge and 18(22.2%) had complex fractures, with 69(85.2%) concomitant fibular fractures. Overall, 20(24.7%) cases had malrotation out of whom 15(75%) had external and 5(25%) had internal malrotation.

When stratification with respect to site of fracture was done in order to see the effect of site of fracture on outcome variable, it was found to be statistically non-significant (p>0.05). When we saw malrotation with respect to type of fracture, the more complex type fractures were associated with more malrotation (p<0.05). None of the patients had malrotation who had intact fibula (p<0.05). 



IMnailing is the treatment of choice fordisplaced diaphyseal fractures of the tibia in adults.5,6 Clinical manifestations after tibial shaft fractures treatment, regardless of the kind of treatment, are subtle and, most of times remain unperceived.

Rotational mal-alignment is a common but difficult complication to detect radiographically and clinically, and it is often underappreciated. There are many methods to assess the rotational mal-alignment intraoperatively by fluoroscopy and post-operatively by computed tomography (CT) scan.3,7 Malrotation is often determined indirectly by fluoroscopy like obtaining the true AP view of knee and Mortis view of ipsilateral ankle and measuring the difference in angle between them. Certain fracture patterns are at high risk for malrotation like transverse, segmental comminuted and fractures associated with ipsilateral fibular fracture. Clinical assessment is an inconsistent method of judging rotation. Assessing rotation by comparing the injured extremity with the normal extremity leads to missed malrotation.

Rotational deviation after IMnail insertion is seldom reported, but literature shows an incidence ranging from 0%to 15% when clinically assessed6 and even upto 30% in some stdues3,7 that showed tibial rotation by means of CT on tibial shaft fractures treated with blocked IMnail and suggestedthat over 20% of the patients developed tibial rotation above 10° when measured by CT. In our study it was 24.7% which is in accordance with literature. 

Other studies7,8 demonstrated that the injury pattern mayinfluence results. High-energy, comminuted fractures, significant deviations of bone fragments and distal third fractures seem topredispose patients to rotational deformities. Also, in our study complex type of fractures were associated with more severe rotational mal-alignment after IMnailing of tibia. It was also observed in our study that an intact fibula prevented rotational mal-alignment. It is believed that rotational mal-alignment of the lower extremity can affect knee and ankle joints biomechanics and may consequently lead to the development and progression of degenerative changes. 

Also, two separate studies reported that tibial mal-alignment was associated with poor functional outcomes.9 Despite these reports, there are several other studies that found no or poor correlation between malunion and osteoarthritis. One study10 demonstrated that there was no correlation between tibialmalrotation and arthrosis.

We believe that our study had an acceptable sample size, but it was performed over a short period of time. A clinical and biomechanical long-term follow-up study on the malrotated group would be helpful to improve the insight generated by our study about the effects of tibial malrotation on the patient\'s gait and quality of life.



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