Comparison between clinical and immunological features of scleroderma with and without interstitial lung disease Authors Muhammad Salman Mushtaq Department of Rheumatology, Pakistan Atomic Energy Commission General Hospital, Islamabad, Pakistan Haris Gul Department of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Pakistan Muhammad Umer Daraz Department of Family Medicine, Holy Family Hospital, Rawalpindi, Pakistan Muhammad khan Department of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Pakistan. Saba Samreen Department of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Pakistan. DOI: https://doi.org/10.47391/JPMA.20173 Keywords: Systemic sclerosis, Scleroderma, Interstitial lung disease Abstract The study was conducted at the Fauji Foundation Hospital, Rawalpindi, Pakistan, from January 1, 2023, to December 31, 2023, and comprised 20 female patients ages 18-55 years having scleroderma. Overall, 14(70%) patients had diffuse scleroderma and 6(30%) had limited scleroderma. The patients with interstitial lung disease were placed in group 1, while those without interstitial lung disease were placed in group 2. Intergroup difference was significant with respect to palpitations, dysphagia, early satiety/reflux, constipation, pulp atrophy, arthritis, tendon friction rubs, digital pitting, digital ulcers, joint contractures, hypertension, positive anti-topoisomerase I antibody, and pulmonary hypertension (p<0.05). Key Words: Systemic sclerosis, Scleroderma, Interstitial lung disease. Downloads Full Text Article Published 2025-08-26 How to Cite Muhammad Salman Mushtaq, Haris Gul, Muhammad Umer Daraz, Muhammad khan, & Saba Samreen. (2025). Comparison between clinical and immunological features of scleroderma with and without interstitial lung disease. Journal of the Pakistan Medical Association, 75(09), 1445–1449. https://doi.org/10.47391/JPMA.20173 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 09 (2025): SEPTEMBER Section SHORT REPORT License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.