Endoscopic resection of lateral spreading tumours in the distal descending segment of duodenum: a rare case report Authors Qi Yao Tianjin First Central Hospital, Tianjin, China Xingming Ji Tianjin First Central Hospital, Tianjin, China Ye Wang Tianjin First Central Hospital, Tianjin, China DOI: https://doi.org/10.47391/JPMA.20313 Keywords: Duodenal tumour, adenoma, intraepithelial neoplasia, digestive system endoscopic surgery Abstract This case reports a patient whose chief complaint was black stool for one month. The white light endoscopic image showed a lesion in the distal proximal horizontal part of the descending duodenum, identified as laterally spreading tumours, non-granular type, flat-elevated type (LST-NG-F). The pathological diagnosis was tubular villous adenoma with high-grade intraepithelial neoplasia. Endoscopic narrow-band imaging revealed disordered mucosal glandular duct openings, disrupted mucosal microvascular arrangement, and a clear boundary between the pathological tissue and the surrounding tissue. After obtaining informed consent, the surgical resection was performed using a treatment strategy involving rubber band ligature and electrotomy. A resection specimen measuring 1.4×2cm was obtained, with negative postoperative resection margins. Keywords: Duodenal tumour, adenoma, intraepithelial neoplasia, digestive system endoscopic surgery. Downloads Full Text Article Published 2025-08-26 How to Cite Yao, Q., Ji, X., & Wang, Y. (2025). Endoscopic resection of lateral spreading tumours in the distal descending segment of duodenum: a rare case report. Journal of the Pakistan Medical Association, 75(09), 1456–1458. https://doi.org/10.47391/JPMA.20313 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 09 (2025): SEPTEMBER Section CASE REPORT License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.