Porencephalic cyst as a cause of seizures in adults: a rare case report using MRI and cerebral angiography methods Authors Muhammad Yunus Amran Department of Neurology, Hasanuddin University, Makassar, Indonesia David Christian Haurissa Department of Neurology, Hasanuddin University, Makassar, Indonesia Gita Vita Soraya Department of Neurology, Hasanuddin University, Makassar, Indonesia DOI: https://doi.org/10.47391/JPMA.25-21308 Keywords: MRI of the head, Cerebral angiography, Porencephalic cyst, Seizure Abstract A porencephalic cyst is a rare intracranial lesion characterised by a cerebrospinal fluid-filled cavity within the cerebral hemisphere, typically surrounded by gliotic or spongiotic white matter. These cysts often present with neurological symptoms such as seizures, developmental delays, or motor impairments, depending on their size and location. We present the case of a 19-year-old male with a three-month history of recurrent seizures. Initial management with valproic acid led to significant improvement, with the patient remaining seizure-free during follow-up. Cerebral MRI revealed a porencephalic cyst with a mural nodule in the left temporo-occipital region; however, angiographic studies demonstrated no vascular abnormalities. Treatment approaches for porencephalic cysts are primarily symptomatic, including the use of antiepileptic medications and physiotherapy to address motor deficits. Surgical intervention may be considered in cases complicated by hydrocephalus or raised intracranial pressure. This case underscores the importance of tailored management strategies in achieving optimal outcomes. Keywords: MRI of the head, Cerebral angiography, Porencephalic cyst, Seizure. Downloads Full Text Article Published 2025-11-22 How to Cite Amran, M. Y., Haurissa, D. C., & Soraya, G. V. (2025). Porencephalic cyst as a cause of seizures in adults: a rare case report using MRI and cerebral angiography methods. Journal of the Pakistan Medical Association, 75(12), 1966–1969. https://doi.org/10.47391/JPMA.25-21308 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 12 (2025): DECEMBER Section CASE REPORT License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.