A giant retroperitoneal liposarcoma encasing vital organs: A case report Authors Adeena Azam Department of Surgery, Jinnah Hospital, Lahore, Pakistan Amna Faheem Mufti Final Year MBBS Student, Allama Iqbal Medical College, Lahore, Pakistan Faizan Masood Department of Medicine, Jinnah Hospital, Lahore, Pakistan Hafiz Usman Azeem Department of Surgery, Jinnah Hospital, Lahore, Pakistan DOI: https://doi.org/10.47391/JPMA.21600 Keywords: liposarcoma, Retroperitoneal liposarcoma Abstract Liposarcoma is the most common primary malignant tumour of the retroperitoneum. As the retroperitoneum is a large space, these tumours can grow significantly before diagnosis. In this case, a 67-year-old male was admitted to a hospital with the complaint of weight loss and abdominal distension. A palpable mass was detected on physical examination, the A scan of this showed it to be retroperitoneal, heterogenous, with multiple septations, calcifications and solid components. It was removed successfully via midline incision. Liposarcoma is derived from adipose tissue and is a soft tissue sarcoma. In most cases, retroperitoneal liposarcoma presents as a painless mass, evident on physical examination. These tumours can go undetected for long periods, as symptoms usually arise only when the mass becomes significantly large. Symptoms include abdominal pain and constipation. Surgical resection is the mainstay of treatment for liposarcoma. Special care must be taken to preserve abdominal organs, which may be difficult considering the size of the mass, especially in resource-limited environments. Keywords: Liposarcoma, retroperitoneal liposarcoma. Downloads Full Text Article Published 2025-08-26 How to Cite Adeena Azam, Mufti, A. F., Faizan Masood, & Hafiz Usman Azeem. (2025). A giant retroperitoneal liposarcoma encasing vital organs: A case report. Journal of the Pakistan Medical Association, 75(09), 1465–1467. https://doi.org/10.47391/JPMA.21600 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 09 (2025): SEPTEMBER Section CASE REPORT License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.