Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy

Authors

  • Syeda Hadia Najam Department of Nuclear Medicine, Shaukat Khanum Memorial Trust, Lahore, Pakistan;
  • Xain Tauqeer Third year Student, Rashid Latif Medical college, Lahore, Pakistan;
  • Aamna Hassan Department of Nuclear Medicine, Shaukat Khanum Memorial Trust, Lahore, Pakistan;
  • Kashif Siddique Department of Radiology, Shaukat Khanum Memorial Trust, Lahore, Pakistan.

DOI:

https://doi.org/10.47391/JPMA.25-23

Abstract

Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvement
and variable visceral manifestations. Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosis
and disease mapping. ECD’s course depends on extraosseous involvement, with potential complications including heart
and renal failure. We present the case of ECD with bilateral leg pain and orbital involvement. Imaging revealed mixed sclerotic
and lytic skeletal lesions, cerebellar lesions, intraorbital soft tissue masses, mediastinal and retroperitoneal infiltration.
Keywords: Erdheim-Chester Disease (ECD), Skeletal and Visceral Involvement, Tc-99m MDP Bone Scintigraphy

Downloads

Published

2025-02-23

How to Cite

Syeda Hadia Najam, Xain Tauqeer, Aamna Hassan, & Kashif Siddique. (2025). Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy. Journal of the Pakistan Medical Association, 75(03), 512–513. https://doi.org/10.47391/JPMA.25-23

Issue

Vol. 75 No. 03 (2025): MARCH

Section

IMAGING CORNER

License

Copyright (c) 2025 Journal of the Pakistan Medical Association

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.