Ascites in Breast Cancer: Progression from Negative Cytology to Avid Peritoneal Involvement Authors Duraksh Arshad Department of Nuclear Medicine Final year elective student Sana Munir Gill Department of Nuclear Medicine Final year elective student Taha Mehmood Department of Nuclear Medicine,Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore. Aamna Hassan Department of Nuclear Medicine Final year elective student DOI: https://doi.org/10.47391/JPMA.25-74 Abstract Malignant ascites is caused by various factors such as lymphatic obstruction, increased vascular permeability and immuneresponse. It presents a significant clinical challenge to the treating physicians considering limited treatment options resultingin increased morbidity and mortality. It is mostly associated with gastrointestinal, gynaecological, breast, hepatobiliary, andlung carcinomas. Paracentesis is usually important in determining the quantity and etiology of ascites. However, unlikeconventional radiological imaging, 18F-FDG PET-CT can act as an early pointer towards its diagnosis. We present a case ofbreast ovarian syndrome highlighting the utility of hybrid nuclear imaging in solving this diagnostic dilemma.Keywords: Malignant ascites, breast cancer, cytology. Downloads Full Text Article Published 2025-08-26 How to Cite Duraksh Arshad, Sana Munir Gill, Taha Mehmood, & Aamna Hassan. (2025). Ascites in Breast Cancer: Progression from Negative Cytology to Avid Peritoneal Involvement. Journal of the Pakistan Medical Association, 75(09), 1480–1481. https://doi.org/10.47391/JPMA.25-74 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 09 (2025): SEPTEMBER Section IMAGING CORNER License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.