The Flavonoids Hesperidin and Diosmin: Adjuvant Therapy for Obesity

Abstract

The flavonoids are polyphenolic plant products,
characterized by a 15-carbon skeleton which includes two
benzene rings. Two active flavonoids, diosmin and
hesperidin, are used as venotonic and vasculoprotective
agents in clinical practice. They are indicated for the
management of varicose veins, chronic venous
insufficiency and haemorrhoids. They help improve
circulatory tone, reduce inflammation, strengthen venous
walls, and alleviate symptoms such as discomfort, pain and
swelling. In this communication, we explore their potential
use in obesity, especially obesity related oedema
(obestasis).
Keywords: Daflon, lymphatic, obesity, oedema,
overweight, venous disorders