Role of 68Ga-DOTA-TOC PET/CT in the Evaluation of Meningiomas with Osseous Involvement

Authors

  • Sharjeel Usmani Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat Oman;Hull Molecular Imaging and Research Center, UK
  • Syed Furqan Hashmi Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat Oman;
  • Anjali Jain Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat Oman;
  • Khulood Al Riyami Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat Oman;
  • Rashid al Sukaiti Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat Oman;
  • Najeeb Ahmed Hull Molecular Imaging and Research Center, UK
  • Muhammad Shahzad Shamim Section of Neurosurgery, Aga Khan University hospital, Karachi, Pakistan.

DOI:

https://doi.org/10.47391/JPMA.26-14

Abstract

Meningiomas with osseous involvement present unique
diagnostic and therapeutic challenges due to their variable
patterns of bone remodelling, hyperostosis, and direct
bone infiltration. While MRI and CT remain the standard
imaging modalities for evaluating soft-tissue extension and
bony architecture respectively, they often fall short in
accurately distinguishing true tumour invasion from
reactive changes, particularly in complex skull-base and
calvarial locations. 68Ga-DOTA-TOC PET/CT represents a
pivotal advancement in the imaging of meningiomas with
osseous involvement, enhancing diagnostic accuracy,
enabling multimodality management, and supporting
personalized therapeutic strategies.
Keywords: 68Ga-DOTA PET/CT; meningiomas; radiotherapy
planning

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Published

2026-01-27

How to Cite

Sharjeel Usmani, Syed Furqan Hashmi, Anjali Jain, Khulood Al Riyami, Rashid al Sukaiti, Najeeb Ahmed, & Muhammad Shahzad Shamim. (2026). Role of 68Ga-DOTA-TOC PET/CT in the Evaluation of Meningiomas with Osseous Involvement. Journal of the Pakistan Medical Association, 76(02), 272–274. https://doi.org/10.47391/JPMA.26-14

Issue

Vol. 76 No. 02 (2026): FEBRUARY

Section

EVIDENCE BASED NEURO-ONCOLOGY

License

Copyright (c) 2026 Journal of the Pakistan Medical Association

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This work is licensed under a Creative Commons Attribution 4.0 International License.