A histopathological and epidemiological study of urothelial carcinoma at a tertiary care centre in Peshawar, Pakistan

Authors

  • Saria Saeed Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan
  • Danyal Khan Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan
  • Shah Faisal Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan
  • Fozia Rauf Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan
  • Muhammad Owais Ali Department of Surgery, Peshawar Medical College, Riphah International University, Peshawar, Pakistan
  • Asif Rehman Department of Community Health Sciences, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

DOI:

https://doi.org/10.47391/JPMA.9546

Keywords:

Carcinoma, Urinary bladder, Cancer, Neoplasm, Urothelial

Abstract

Bladder cancer is the ninth leading cause of death worldwide and 14th leading cause of death in Pakistan. The objective of this study was to determine the frequency of urothelial carcinoma in various age groups, its gender distribution, and grades. A total of 131 cases of urothelial carcinoma, received at Department of Pathology, Peshawar Medical College, Peshawar, between January 2017 to December 2022, were included in the study; of them 107 (81.6%) were males while 24 (18.3%) were females with a mean age of 62±13 years. The most common histological subtype was papillary urothelial carcinoma in 117(89.3%) cases, followed by Squamous and Glandular in 5(3.8%) cases. Majority of the urothelial carcinoma with high grade showed a statistically significant relation with muscle invasion (n=38, 50.66%). Males were four times more likely to have urothelial carcinoma while older age groups were more likely to have high grade urothelial carcinoma.

Keywords: Carcinoma, Urinary bladder, Cancer, Neoplasm, Urothelial.

Author Biographies

Saria Saeed, Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Lecturer, Department of Pathology, Peshawar Pedical College

Danyal Khan, Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

 FCPS Trainee, AFIP, Pakistan.         

Shah Faisal, Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Lecturer Pathology, Peshawar Medical College 

   

Fozia Rauf, Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Professor, Pathology. Peshawar Medical College, Pakistan.

Muhammad Owais Ali, Department of Surgery, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

FCPS Trainee Surgery, Peshawar Medical College

Published

2024-05-24

How to Cite

Saeed, S., Khan, D., Faisal, S., Rauf, F., Ali, M. O., & Rehman, A. (2024). A histopathological and epidemiological study of urothelial carcinoma at a tertiary care centre in Peshawar, Pakistan. Journal of the Pakistan Medical Association, 74(6), 1160–1162. https://doi.org/10.47391/JPMA.9546

Issue

Section

Short Communication